Olig2 Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comOlig2 Polyclonal Antibody for Mouse(Mus musculus)

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Olig2 (Gene name),

Oligodendrocyte transcription factor 2 (Protein name ), OLIG2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Olig2;

Protein name:

Oligodendrocyte transcription factor 2(Oligo2);

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with NKX2-2.

Function:

Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development.

Subcellular Location:

Nucleus Cytoplasm The NLS contained in the bHLH domain could be masked in the native form and translocation to the nucleus could be mediated by interaction either with class E bHLH partner protein or with NKX2-2.

Protein Attributes:

Sequence length:

323

Sequence:

50:

100:

150:

200:

250:

300:

323:

PPPHHHVSAM | GAGTLPRLTS | DAK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.37289

KEGG:

mmu:50913

SMR:

Q9EQW6

String:

Q9EQW6

Pfam:

PF00010

Uniprot:

Q9EQW6

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ELISA Kit for Mouse Oligo2

Cat.:

E15290h

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Mouse Oligo2

Cat.:

E15290c

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MSDS:

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Packing:

96T

ELISA Kit for Mouse Oligo2

Cat.:

E15290m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Oligo2

Cat.:

U15290c

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Oligo2

Cat.:

U15290m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Oligo2

Cat.:

U15290h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Oligo2

Cat.:

P15290Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Oligo2

Cat.:

P15290Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Oligo2

Protein for Mouse Oligo2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3."
Takebayashi H. , Yoshida S. , Sugimori M. , Kosako H. , Kominami R. , Nakafuku M. , Nabeshima Y.
Mech. Dev.99:143-148(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
strain: C57BL/6.
tissue: Brain.
2.

"Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors."
Zhou Q. , Wang S. , Anderson D.J.
Neuron25:331-343(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];DEVELOPMENTAL STAGE
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6.
tissue: Brain.
4.

"Sonic hedgehog-regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system."
Lu Q.R. , Yuk D.-I. , Alberta J.A. , Zhu Z. , Pawlitzky I. , Chan J.A. , McMahon A.P. , Stiles C.D. , Rowitch D.H.
Neuron25:317-329(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY SHH
5.

"Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection."
Lu Q.R. , Sun T. , Zhu Z. , Ma N. , Garcia M. , Stiles C.D. , Rowitch D.H.
Cell109:75-86(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
6.

"The basic helix-loop-helix factor olig2 is essential for the development of motoneuron and oligodendrocyte lineages."
Takebayashi H. , Nabeshima Y. , Yoshida S. , Chisaka O. , Ikenaka K. , Nabeshima Y.
Curr. Biol.12:1157-1163(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
7.

"Non-overlapping expression of Olig3 and Olig2 in the embryonic neural tube."
Takebayashi H. , Ohtsuki T. , Uchida T. , Kawamoto S. , Okubo K. , Ikenaka K. , Takeichi M. , Chisaka O. , Nabeshima Y.
Mech. Dev.113:169-174(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
8.

"Region-specific and stage-dependent regulation of Olig gene expression and oligodendrogenesis by Nkx6.1 homeodomain transcription factor."
Liu R. , Cai J. , Hu X. , Tan M. , Qi Y. , German M. , Rubenstein J.L.R. , Sander M. , Qiu M.
Development130:6221-6231(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY NKX6-1
9.

"Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex."
Sun T. , Dong H. , Wu L. , Kane M. , Rowitch D.H. , Stiles C.D.
J. Neurosci.23:9547-9556(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NKX2-2;SUBCELLULAR LOCATION

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